Nonetheless, there are some clues that can clearly offer a bit of guidance in judging the likelihood of at least a partial recovery. We next discuss secondary injury and physiologic determinants that Adult anoxic brain in injury targets of therapeutic interventions after HIBI. Their objective was to examine the association between hyperoxia and mortality. While the process will never be easy, the following tips may help to minimize possible tension and conflict:. Augmenting arterial oxygen content is touted as a crucial modifiable factor in optimizing CDO 2 after HIBI, with normobaric hyperoxia being suggested to achieve this goal.